Subcortical MRI volumes in neuroleptic-naive and treated patients with schizophrenia.

  title={Subcortical MRI volumes in neuroleptic-naive and treated patients with schizophrenia.},
  author={Raquel E. Gur and V Maany and P David Mozley and Charlie L. Swanson and W. B. Bilker and Ruben C. Gur},
  journal={The American journal of psychiatry},
  volume={155 12},
  • R. Gur, V. Maany, R. Gur
  • Published 1 December 1998
  • Psychology, Medicine
  • The American journal of psychiatry
OBJECTIVE This study examined whether subcortical volumes of the basal ganglia and thalamus in schizophrenic patients are related to neuroleptic exposure and symptom severity. METHOD Basal ganglia substructures and thalamic volumes were measured with magnetic resonance imaging in 96 patients with schizophrenia (50 men and 46 women) and 128 healthy comparison subjects (60 men and 68 women). Twenty-one of the patients were neuroleptic-naive; of the 75 previously treated patients, 48 had… 

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