Subcompartmentalization of HIV-1 quasispecies between seminal cells and seminal plasma indicates their origin in distinct genital tissues.

@article{Paranjpe2002SubcompartmentalizationOH,
  title={Subcompartmentalization of HIV-1 quasispecies between seminal cells and seminal plasma indicates their origin in distinct genital tissues.},
  author={Shirish Paranjpe and J. M. Craigo and Bruce K. Patterson and Ming Ding and Paulo Feij{\'o} Barroso and Lee Harrison and Ronald C. Montelaro and Phalguni Gupta},
  journal={AIDS research and human retroviruses},
  year={2002},
  volume={18 17},
  pages={1271-80}
}
The mononuclear cells and plasma components of semen from HIV-infected subjects have been shown to contain HIV-1. However, there is very little information as to whether distinct HIV-1 population are present in these two seminal compartments or as to their tissue of origin. Phylogenetic analysis of nucleotide sequences of the C2-V5 region of the HIV-1 gp120 from HIV-1 RNA isolated from seminal cells and seminal plasma of five subjects indicates that the HIV-1 population derived from seminal… CONTINUE READING

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