Subclinical vitamin K deficiency in hemodialysis patients.

  title={Subclinical vitamin K deficiency in hemodialysis patients.},
  author={Rachel M Pilkey and Alexander Ross Morton and Michael B Boffa and Curtis Noordhof and Andrew George Day and Yinghua Su and Lisa M. Miller and Marlys L Koschinsky and Sarah L. Booth},
  journal={American journal of kidney diseases : the official journal of the National Kidney Foundation},
  volume={49 3},
BACKGROUND Subclinical vitamin K deficiency increasingly is associated with extraosseous calcification in healthy adults. Nondietary determinants of vitamin K status include apolipoprotein E (apoE) genotype, which may influence vitamin K transport to peripheral tissues. METHODS Serum phylloquinone concentrations and percentage of uncarboxyated osteocalcin (%ucOC) were measured by means of high-performance liquid chromatography and radioimmunoassay in 142 hemodialysis patients, respectively… CONTINUE READING