Subclinical pulmonary function defects following autologous and allogeneic bone marrow transplantation: relationship to total body irradiation and graft-versus-host disease.

@article{Tait1991SubclinicalPF,
  title={Subclinical pulmonary function defects following autologous and allogeneic bone marrow transplantation: relationship to total body irradiation and graft-versus-host disease.},
  author={R Campbell Tait and Alan Kenneth Burnett and A. Gerry Robertson and Stuart G McNee and B M Riyami and Reginald C Carter and Robin D. Stevenson},
  journal={International journal of radiation oncology, biology, physics},
  year={1991},
  volume={20 6},
  pages={
          1219-27
        }
}
Pulmonary function results pre- and post-transplant, to a maximum of 4 years, were analyzed in 98 patients with haematological disorders undergoing allogeneic (N = 53) or autologous bone marrow transplantation (N = 45) between 1982 and 1988. All received similar total body irradiation based regimens ranging from 9.5 Gy as a single fraction to 14.4 Gy fractionated. FEV1/FVC as a measure of airway obstruction showed little deterioration except in patients experiencing graft-versus-host disease in… CONTINUE READING
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