Subclinical Cushing's syndrome: current concepts and trends.

  title={Subclinical Cushing's syndrome: current concepts and trends.},
  author={George Nikolaos Zografos and Iraklis Perysinakis and Evangeline Vassilatou},
  volume={13 3},
Clinically inapparent adrenal masses which are incidentally detected have become a common problem in everyday practice. Approximately 5-20% of adrenal incidentalomas present subclinical cortisol hypersecretion which is characterized by subtle alterations of the hypothalamic-pituitary-adrenal axis due to adrenal autonomy. This disorder has been described as subclinical Cushing's syndrome, since there is no typical clinical phenotype. The diagnosis of subclinical Cushing's syndrome is based on… CONTINUE READING


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