Subclass responses and their half-lives for antibodies against EBA175 and PfRh2 in naturally acquired immunity against Plasmodium falciparum malaria

@inproceedings{Ismail2014SubclassRA,
  title={Subclass responses and their half-lives for antibodies against EBA175 and PfRh2 in naturally acquired immunity against Plasmodium falciparum malaria},
  author={Hodan Ahmed Ismail and Muyideen K. Tijani and Christine Langer and Linda Reiling and Michael White and James G Beeson and Mats Wahlgren and Roseangela I. Nwuba and Kristina E. M. Persson},
  booktitle={Malaria Journal},
  year={2014}
}
Plasmodium falciparum EBA175 and PfRh2 belong to two main families involved in parasite invasion, and both are potential vaccine candidates. Current knowledge is limited regarding which target antigens and subclasses of antibodies are actually important for protection, and how naturally acquired immunity is achieved. Repeated blood samples were collected from individuals in Nigeria over a period of almost one year. ELISA was used to analyse subclasses of IgG responses. For both EBA175 (region… CONTINUE READING
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