Corpus ID: 27886628

Subchronic treatment of rats with remoxipride fails to modify sigma binding sites in the brain.

@article{Ericson1992SubchronicTO,
  title={Subchronic treatment of rats with remoxipride fails to modify sigma binding sites in the brain.},
  author={H. Ericson and S. Ross},
  journal={European journal of pharmacology},
  year={1992},
  volume={226 2},
  pages={
          157-61
        }
}
  • H. Ericson, S. Ross
  • Published 1992
  • Medicine
  • European journal of pharmacology
  • The effects of 14 days' treatment of rats with haloperidol, remoxipride or both combined on the sigma binding sites in whole brain and liver were determined. The compounds were given subcutaneously via osmotic minipumps at a dose of 0.25 mg/rat/day (corresponding to about 1 mg/kg body weight/day at start) for haloperidol and 2.5 mg/rat/day (10 mg/kg/day) for remoxipride hydrochloride. The sigma recognition sites were determined after a washout period of 2 days with the radioligand [3H](+)-N… CONTINUE READING
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