Subchronic peroral toxicity of triethylene glycol in the Fischer 344 rat.


Ethylene and diethylene glycols produce systemic toxicity, including nephrotoxicity, by acute and repeated po dosing. To determine the potential for triethylene glycol (TEG; CAS Number 112-27-61) to produce nephrotoxicity, or other organ/tissue injury, a subchronic (90-d) study was conducted by continuous inclusion of TEG in the diet of Fischer 344 rats… (More)


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