Subchronic effects of perfluorooctanesulfonate exposure on inflammation in adult male C57BL/6 mice.

@article{Dong2012SubchronicEO,
  title={Subchronic effects of perfluorooctanesulfonate exposure on inflammation in adult male C57BL/6 mice.},
  author={Guanghui Dong and Ying-hua Zhang and Li Zheng and Zai-fu Liang and Yi-he Jin and Qin-cheng He},
  journal={Environmental toxicology},
  year={2012},
  volume={27 5},
  pages={285-96}
}
Previous studies indicate that exposure to perfluorooctanesulfonate (PFOS), a ubiquitous and highly persistent environmental contaminant, induces immunotoxicity in mice. However, few studies have specifically assessed the effects of PFOS on inflammation. This study utilized a standard 60-day oral exposure period to assess the effects of PFOS on the response of inflammatory cytokines [tumor necrosis factor α (TNF-α), interleukin-1 β (IL-1β), and interleukin-6 (IL-6)]. Adult male C57BL/6 mice… CONTINUE READING
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