Subcellular localization of type 1 cannabinoid receptors in the rat basal ganglia

@article{Mtys2006SubcellularLO,
  title={Subcellular localization of type 1 cannabinoid receptors in the rat basal ganglia},
  author={Ferenc M{\'a}ty{\'a}s and Yevgenij Yanovsky and Ken Mackie and Wolfgang Kelsch and Ulrich Misgeld and Tam{\'a}s F. Freund},
  journal={Neuroscience},
  year={2006},
  volume={137},
  pages={337-361}
}
Endocannabinoids, acting via type 1 cannabinoid receptors (CB1), are known to be involved in short-term synaptic plasticity via retrograde signaling. Strong depolarization of the postsynaptic neurons is followed by the endocannabinoid-mediated activation of presynaptic CB1 receptors, which suppresses GABA and/or glutamate release. This phenomenon is termed depolarization-induced suppression of inhibition (DSI) or excitation (DSE), respectively. Although both phenomena have been reported to be… CONTINUE READING
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