Subcellular localization of the methylcitric-acid-cycle enzymes in propionate metabolism of Yarrowia lipolytica.

@article{Uchiyama1982SubcellularLO,
  title={Subcellular localization of the methylcitric-acid-cycle enzymes in propionate metabolism of Yarrowia lipolytica.},
  author={Hidefumi Uchiyama and Masayoshi Ando and Y Toyonaka and Takafumi Tabuchi},
  journal={European journal of biochemistry},
  year={1982},
  volume={125 3},
  pages={523-7}
}
The subcellular localization of the four characteristic enzymes of the methylcitric acid cycle was studied with glucose-grown as well as n-alkane-grown cells of Yarrowia lipolytica. Microsomes and peroxisomes showed no cycle enzyme activities. The four cycle enzymes were constitutively localized in mitochondria, with the exception of the dual localization of the fourth enzyme, 2-methylisocitrate lyase, in mitochondria and cytoplasm, where the lyase may function to supply pyruvate (the end… CONTINUE READING

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