Subcellular localization of caspase-3 activation correlates with changes in apoptotic morphology in MOLT-4 leukemia cells exposed to X-ray irradiation.

Abstract

Caspase-3 is a critical effector caspase for apoptosis, which cleaves proteins, including cytoskeletal and associated proteins, kinases, and members of the Bcl-2 family of apoptosis-related proteins. This leads to changes in apoptotic morphology, such as membrane externalization and cytoplasm and nuclear condensation. It has been reported that pro-caspase-3… (More)

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Cite this paper

@article{Feng2005SubcellularLO, title={Subcellular localization of caspase-3 activation correlates with changes in apoptotic morphology in MOLT-4 leukemia cells exposed to X-ray irradiation.}, author={Yongdong Feng and Junbo Hu and Daxin Xie and Jichao Qin and Yisheng Zhong and Xiaolan Li and Wei Xiao and Jianhong Wu and Deding Tao and M Zhang and Yunfeng Zhu and Yuping Song and Eddie Reed and Qingdi Quentin Li and Jianping Gong}, journal={International journal of oncology}, year={2005}, volume={27 3}, pages={699-704} }