Subcellular localization of angiotensin-converting enzyme in the human alveolar macrophage.

@article{Eklund1987SubcellularLO,
  title={Subcellular localization of angiotensin-converting enzyme in the human alveolar macrophage.},
  author={Anders Eklund and Eleonora Blaschke and Bengt Danielsson},
  journal={Scandinavian journal of clinical and laboratory investigation},
  year={1987},
  volume={47 1},
  pages={47-54}
}
The present investigation was performed in order to elucidate the subcellular localization of angiotensin-converting enzyme (ACE) in human alveolar macrophages. A pure population of alveolar macrophages was obtained by centrifugal elutriation of bronchoalveolar lavage (BAL) fluid from seven sarcoid patients. The cells were homogenized by sonication and the postnuclear supernatant was fractionated on a discontinuous sucrose gradient. Fractions of particulate material were collected and… CONTINUE READING