Subcellular distribution of glutamate decarboxylase in rat olfactory bulb: high content in dendrodendritic synaptosomes.

@article{Quinn1980SubcellularDO,
  title={Subcellular distribution of glutamate decarboxylase in rat olfactory bulb: high content in dendrodendritic synaptosomes.},
  author={Michael R. Quinn and R. H. Cagan},
  journal={Journal of neurochemistry},
  year={1980},
  volume={35 3},
  pages={583-90}
}
The olfactory bulbs in the CNS contain reciprocal dendrodendritic synapses between the granule cells and the secondary dendrites of mitral cells. Based on pharmacologic and electrophysiologic evidence, these synapses are believed to utilize GABA as an inhibitory neurotransmitter. A dendrodendritic synaptosomal fraction has been isolated from rat olfactory bulbs. The upper portion (PB) of the crude nuclear pellet contains 30-40% of the GAD (glutamate decarboxylase) activity of the olfactory bulb… CONTINUE READING

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