Subcellular and subsynaptic localization of group I metabotropic glutamate receptors in the nucleus accumbens of cocaine-treated rats.

@article{Mitrano2008SubcellularAS,
  title={Subcellular and subsynaptic localization of group I metabotropic glutamate receptors in the nucleus accumbens of cocaine-treated rats.},
  author={Darlene A Mitrano and Christopher Arnold and Yoland Smith},
  journal={Neuroscience},
  year={2008},
  volume={154 2},
  pages={653-66}
}
There is significant pharmacological and behavioral evidence that group I metabotropic glutamate receptors (mGluR1a and mGluR5) in the nucleus accumbens play an important role in the neurochemical and pathophysiological mechanisms that underlie addiction to psychostimulants. To further address this issue, we undertook a detailed ultrastructural analysis to… CONTINUE READING