Subcellular Localization of Leptin in Non-tumorous and Adenomatous Human Pituitaries: An Immuno-ultrastructural Study

@article{Vidal2000SubcellularLO,
  title={Subcellular Localization of Leptin in Non-tumorous and Adenomatous Human Pituitaries: An Immuno-ultrastructural Study},
  author={Sergio Vidal and Seth M. Cohen and Eva Horvath and Kalman T Kovacs and Bernd W. Scheithauer and Bartolom{\'e} Burguera and Ricardo V. Lloyd},
  journal={Journal of Histochemistry & Cytochemistry},
  year={2000},
  volume={48},
  pages={1147 - 1152}
}
  • Sergio Vidal, Seth M. Cohen, +4 authors Ricardo V. Lloyd
  • Published in
    The journal of histochemistry…
    2000
  • Biology, Medicine
  • Journal of Histochemistry & Cytochemistry
  • Leptin is a key mediator in the maintenance of neuroendocrine homeostasis. Recently, leptin and leptin receptor expression were demonstrated in non-tumorous and adenomatous human pituitaries. This study was performed to determine the subcellular localization of leptin in human adenohypophyses (n = 3) and in various types of pituitary adenoma (n = 16). Immunoelectron microscopy showed leptin immunolabeling in most hormone-producing cells of the human non-tumorous adenohypophysis, but not in… CONTINUE READING

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