Subcellular Distribution of a Voltage-Gated Potassium Channel : the Effect of Localization on Channel Function

Abstract

Voltage-gated potassium channels are primary determinants of cellular excitability in the mammalian nervous system. The localization of these channels to distinct cellular compartments influences components of neuronal function, including resting membrane potential, action potential characteristics and neurotransmitter release. Thus, understanding the… (More)

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