Subarachnoid hemorrhage-induced upregulation of the 5-HT1B receptor in cerebral arteries in rats.

@article{HansenSchwartz2003SubarachnoidHU,
  title={Subarachnoid hemorrhage-induced upregulation of the 5-HT1B receptor in cerebral arteries in rats.},
  author={Jacob A Hansen-Schwartz and Natalie L\ovland Hoel and Cang-Bao Xu and N. Aa. Svendgaard and Lars Edvinsson},
  journal={Journal of neurosurgery},
  year={2003},
  volume={99 1},
  pages={115-20}
}
OBJECT Cerebral vasospasm following subarachnoid hemorrhage (SAH) leads to reduced blood flow in the brain. Inspired by organ culture-induced changes in the receptor phenotype of cerebral arteries, the authors investigated possible changes in the 5-hydroxytryptamine (HT) receptor phenotype after experimental SAH. METHODS Experimental SAH was induced in rats by using an autologous prechiasmatic injection of arterial blood. Two days later, the middle cerebral artery (MCA), posterior… CONTINUE READING
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