Subacute toxicity study of the methanolic seed extract of Buchholzia coriacea (Capparaceae) in rats

The methanol extract of Buchholzia coriacea seed has shown some anti-trypanosomal activity against Trypanosoma brucei brucei. The acute toxicity test of this extract showed no signs of toxicity. This present study was designed to assess its sub-acute toxicity in rats. Rats of both sexes were dosed daily with 125, 250 and 500 mg/kg body weight of the extract… (More)