Subacute toxicity of Zwittergent administered intramuscularly.


In order to assess the systemic toxicity of Zwittergent 3-14, a detergent used in the protein-detergent complex vaccines for its attractive immunogenic properties, a subacute toxicity study was performed. In this 4-week toxicity experiment five female and five male rats per group were injected intramuscularly with 0.25 ml of 0, 75, 750 and 7500 micrograms… (More)


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@article{Speijers1989SubacuteTO, title={Subacute toxicity of Zwittergent administered intramuscularly.}, author={Gerrit J A Speijers and L. H. J. C. Danse and Magda A. M. Krajnc-Franken and Florian van Leeuwen and P W Helleman and E. Coen Beuvery and J. G. M. Vos and C A vd Heijden}, journal={Vaccine}, year={1989}, volume={7 4}, pages={364-8} }