Subacute sclerosing panencephalitis: more cases of this fatal disease are prevented by measles immunization than was previously recognized.

@article{Bellini2005SubacuteSP,
  title={Subacute sclerosing panencephalitis: more cases of this fatal disease are prevented by measles immunization than was previously recognized.},
  author={William J. Bellini and Jennifer S. Rota and Luis E. Lowe and Russell S. Katz and Paul Richard Dyken and Sherif R. Zaki and W. J. Shieh and Paul A Rota},
  journal={The Journal of infectious diseases},
  year={2005},
  volume={192 10},
  pages={1686-93}
}
BACKGROUND The most severe sequela of measles virus infection is subacute sclerosing panencephalitis (SSPE), a fatal disease of the central nervous system that generally develops 7-10 years after infection. From 1989 through 1991, a resurgence of measles occurred in the United States, with 55,622 cases of measles reported. The purpose of the present study was to identify cases of SSPE that were associated with the resurgence of measles and to calculate the risk of developing SSPE. METHODS… CONTINUE READING

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Genetic analysis of measles viruses isolated in the United States between 1989 and 2001 : absence of an endemic genotype since 1994

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