Subacute dementia with necrotising encephalitis selectively involving the fornix and splenium: Retrograde development of Alzheimer's neurofibrillar tangles in the subiculum

@article{Yamamoto1990SubacuteDW,
  title={Subacute dementia with necrotising encephalitis selectively involving the fornix and splenium: Retrograde development of Alzheimer's neurofibrillar tangles in the subiculum},
  author={Tadashi Yamamoto and Hirotsugu Kurobe and Junichiro Kawamura and Shigeo Hashimoto and Michikazu Nakamura},
  journal={Journal of the Neurological Sciences},
  year={1990},
  volume={96},
  pages={159-172}
}
An elderly woman developed subacute progressive dementia with predominant impairment in recent memory and CT findings indicating an enhancing lesion near the splenium of the corpus callosum. Autopsy four months after the onset of the symptoms revealed necrotising encephalitis selectively involving the bilateral fornices and the adjacent splenium. Degeneration was marked in the contiguous right fimbria hippocampi. Particularly numerous Alzheimer's neurofibrillar tangles (NFTs) were present in… CONTINUE READING
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