Subacute Hemodynamic Effects of Nebivolol in Man at Rest and During Exercise

  title={Subacute Hemodynamic Effects of Nebivolol in Man at Rest and During Exercise},
  author={J. de Cree and H. Geukens and C. Cobo and H. Verhaegen},
  pages={440 - 448}
  • J. de Cree, H. Geukens, +1 author H. Verhaegen
  • Published 1987
  • Medicine
  • Angiology
  • In a subacute experiment 7 apparently healthy volunteers received a daily oral dose of 5 mg nebivolol for seven days, followed by a seven-day washout period with placebo. From the first day during treatment with nebivolol, peak exercise heart rate and systolic blood pressure, as measured during a standard ized submaximal treadmill exercise, significantly decreased by 15% and 19% respectively. A prolonged treatment for one week did not further increase the response of exercise heart rate and… CONTINUE READING
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