Subacute (28 day) Toxicity of Surfactin C, a Lipopeptide Produced by Bacillus subtilis, in Rats

  title={Subacute (28 day) Toxicity of Surfactin C, a Lipopeptide Produced by Bacillus subtilis, in Rats},
  author={Y. Hwang and M. Kim and In-Bae Song and B. Park and Jong-Hwan Lim and S. Park and H. Yun},
  journal={Journal of Health Science},
  • Y. Hwang, M. Kim, +4 authors H. Yun
  • Published 2009
  • Biology
  • Journal of Health Science
  • Surfactin C, produced by acillus subtilis isolated from Korean soybean paste, was given to Sprague-Dawley rats of both sexes at dose of 500, 1000 or 2000 mg/kg for 28 days. There were no surfactin C-related toxicities in survival, clinical signs ,a ndhematological parameters in the experimental period. The highest dose of surfactin C showed the decrease in body weight gain despite normal food and water consumptions and the increase in relative liver weight. alanine aminotransferase (ALT… CONTINUE READING
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