Sub types of α2-adrenoceptors: Pharmacological and molecular biological evidence converg

  title={Sub types of α2-adrenoceptors: Pharmacological and molecular biological evidence converg},
  author={D. B. Bylund},
  journal={Trends in Pharmacological Sciences},
  • D. B. Bylund
  • Published 1988
  • Biology
  • Trends in Pharmacological Sciences
  • Abstract A review of the available evidence indicates that α 2 -adrenoceptors are not a homogeneous class of receptors, but can be subdivided into several subtypes based on their pharmacological characteristics. The recent cloning of the DNA for two α 2 -receptor subtypes provides an independent validation of the pharmacological data. David Bylund targues that the combination of cloning and pharmacological techniques should soon provide for a consistent classification scheme for α 2… CONTINUE READING
    340 Citations
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