Sub-clinical atrophy of the retinal nerve fibre layer in multiple sclerosis.

@article{Pueyo2010SubclinicalAO,
  title={Sub-clinical atrophy of the retinal nerve fibre layer in multiple sclerosis.},
  author={Victoria Pueyo and Jos{\'e} Ram{\'o}n Ara and Carmen Alm{\'a}rcegui and Jes{\'u}s Hern{\'a}ndez Martin and Noem{\'i} G{\"u}erri and Ernesto Garc{\'i}a and Luis Emilio Pablo and Francisco Manuel Honrubia and Francisco Javier Fern{\'a}ndez},
  journal={Acta ophthalmologica},
  year={2010},
  volume={88 7},
  pages={748-52}
}
PURPOSE This study aimed to evaluate the presence of abnormalities in the retinal nerve fibre layer (RNFL) in multiple sclerosis (MS) patients with normal ophthalmic examination, and to compare the ability of optical coherence tomography (OCT) and scanning laser polarimetry (GDx) to detect axonal loss. METHODS Patients with MS and disease-free controls were invited to enrol in the study from 1 February 2007 to 30 June 2008. Ophthalmic examination, including evaluation of visual acuity (VA… CONTINUE READING

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