Sub-atomic resolu0on X-ray diffrac0on of the SH3 domain from the post-synap0c density protein Shank3

  • Srinivas Kumar Ponnaa, Tobias M. Boeckersb, Petri Kursulaac
  • Published 2016


The post-synapBc density mulBdomain scaffolding proteins of the Shank family are structurally poorly characterised. The Shank family consists of three members, and domain-specific interacBons of Shank are involved in forming a network of proteins at the post-synapBc region for intracellular signalling and cellular scaffolding. While X-ray crystallography… (More)


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