Sub‐lingual Immunotherapy: World Allergy Organization Position Paper 2009

  title={Sub‐lingual Immunotherapy: World Allergy Organization Position Paper 2009},
  author={Giorgio Walter Canonica and Jean Bousquet and Thomas B. Casale and Richard F. Lockey and Carlos E. Baena-Cagnani and Ruby Pawankar and Paul Charles Potter and Philippe Jean Bousquet and Linda S. Cox and Stephen R. Durham and Harold S. Nelson and Giovanni Passalacqua and Dermot Ryan and Jan L. Brożek and Enrico Compalati and Ronald Dahl and Lu{\'i}s Delgado and Roy Gerth van Wijk and Richard G. Gower and Dennis K. Ledford and Nelson Rosario Filho and Erkka J Valovirta and Osman M. Yusuf and Torsten Zuberbier and Wahiduzzaman Akhanda and Ra{\'u}l L{\'a}zaro Castro Almarales and Ignacio J. Ansotegui and Floriano Bonifazi and Johan Ceuppens and Tom{\'a}s Chivato and Darina Dimova and Diana Mihaela Dumitrascu and Luigi Fontana and Constance H. Katelaris and Ranbir Kaulsay and Piotr Kuna and D{\'e}sir{\'e}e E Larenas-Linnemann and Manolis Manoussakis and Krist{\'o}f N{\'e}k{\'a}m and Carlos Nunes and Robyn Elizabeth O'Hehir and Jos{\'e} Mar{\'i}a Olaguibel and Nerin Bahceciler Onder and Jung Won Park and Alfred Priftanji and Robert Puy and Luis Sarmiento and Glenis K. Scadding and Peter Schmid‐Grendelmeier and Ester Seberov{\'a} and Revaz Sepiashvili and Dirceu Sol{\'e} and Alkis G. Togias and Carlo Tomino and Elina M. Toskala and Hugo Van Beever and Stefan Vieths},
Co-Authors: Wahiduzzaman Akhanda, Raul Castro Almarales, Ignacio Ansotegui, Floriano Bonifazi, Jan Ceuppens, Tomás Chivato, Darina Dimova, Diana Dumitrascu, Luigi Fontana, Constance HKatelaris, Ranbir Kaulsay, Piotr Kuna, Dèsirée Larenas-Linnemann, Manolis Manoussakis, Kristof Nekam, Carlos Nunes, Robyn O’Hehir, José M Olaguibel, Nerin Bahceciler Onder, JungWon Park, Alfred Priftanji, Robert Puy, Luis Sarmiento, Glenis Scadding, Peter Schmid-Grendelmeier, Ester Seberova, Revaz Sepiashvili… 

How to design and evaluate randomized controlled trials in immunotherapy for allergic rhinitis: an ARIA‐GA2LEN statement

How to design and evaluate randomized controlled trials in immunotherapy for allergic rhinitis: an ARIA‐GA2LEN statement is described.

Practical guide to skin prick tests in allergy to aeroallergens

The Practical guide to skin prick tests in allergy to aeroallergens 2012; 67: 18–24 is cited.


S ON THE TOPIC OF THE DISSERTATION I. Tokodi Margaréta, Bella Zsolt, Csábi Eszter, Kiricsi Ágnes, Kollár Edit, Rovó László (2014). Az egyszeri allergéndózis (nazális provokáció) hatása a fizikai

Sublingual immunotherapy not effective in house dust mite–allergic children in primary care

Sublingual immunotherapy not effective in house dust mite–allergic children in primary care, Pediatr Allergy Immunol 2011.

Sublingual immunotherapy: A focused allergen immunotherapy practice parameter update.

  • M. GreenhawtJ. Oppenheimer D. Wallace
  • Medicine
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology
  • 2017

Allergen Specific Immunotherapy for Allergic Rhinitis

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Clinical Implications and Facts About Allergic Rhinitis (AR) in Children

Zorica Zivkovic1,2, Sofija Cerovic2, Ivana Djuric-Filipovic1, Zoran Vukasinovic3,4, Jasmina Jocic-Stojanovic2 and Aleksandra Bajec-Opancina5 1US Medical School, European University, Belgrade

Sublingual immunotherapy: World Allergy Organization position paper 2013 update

“Raising public awareness about sublingual immunotherapy”, as a need for patients, and strategies to increase awareness of allergen immunotherapy (AIT) among patients, the medical community, all healthcare stakeholders, and public opinion are reported in detail.

Sublingual immunotherapy (SLIT)--indications, mechanism, and efficacy: Position paper prepared by the Section of Immunotherapy, Polish Society of Allergy.

The highest quality evidence supporting the efficacy of SLIT lasting 1-3 years has been provided by the large scale double-blind, placebo-controlled (DBPC) trials for grass pollen extracts, both in children and adults with allergic rhinitis.



Standards for practical allergen‐specific immunotherapy

This work aims to provide a systematic review and meta-analyses of the phytochemical properties of the fruit fly coronavirus which has been implicated in the spread of influenza in Europe and Asia.

Local immunotherapy

Mailing H,-J, Abreu-Nogueira J, Alvarez-Cuesta E, Bjorksten B. Bousquet J, Caillot D, Canonica GW, Passalacqua G, Saxonis-Papageorgiou P, Valovirla E. Local immunotherapy. Allergy 1998: 53: 933-944.

Sublingual immunotherapy for cow's milk protein allergy: a preliminary report

Vervloet D. Hymenoptera ultra-rush venom immunotherapy (210 min): a safety study and risk factors. Clin Exp Allergy 2003;33:58–64. 5. Van der Brempt X, Ledent C, Mairesse M. Accelerated

Injective versus sublingual immunotherapy in Alternaria tenuis allergic patients.

Results are in good agreement with previous reports on SIT and SLIT with other inhalant allergens (mites, grasses), and suggest the potential use of SLIT for Alternaria allergy, mainly in young patients, when there are concerns about the safety of and compliance with the traditional injective therapy.

The efficacy of sublingual immunotherapy for house dust mites respiratory allergy: results of a GA²LEN meta‐analysis

Investigation of the efficacy of SLIT with house dust mite (HDM) extracts in allergic patients suffering from AR and AA through an updated reassessment of randomized controlled trials suggests that more data are needed, derived from large‐population‐based high quality studies, and corroborated by objective outcomes.

A double‐blind, placebo‐controlled study of immunotherapy with grass‐pollen extract Alutard SQ during a 3–year period with initial rush immunotherapy

The efficacy and safety of immunotherapy with grass pollen make it possible to consider this treatment fundamental in patients with asthma and/or monosensitized allergic rhinitis, and there was no relationship between clinical improvement and the range of specific immunoglobulin E values.

Anaphylaxis by latex sublingual immunotherapy

In the present communication, a 36-year-old woman with latex allergy, affected by urticaria and asthma challenged by the handling or the exposition to latex articles and treated with SLIT is reported, confirming that rare cases of systemic reactions, sometime severe, have been observed during SLIT.

Sublingual‐swallow immunotherapy (SLIT) in patients with asthma due to house‐dust mites: a double‐blind, placebo‐controlled study

SLIT in house‐dust‐mite‐related asthma has a good safety profile and improves respiratory function, bronchial hyperreactivity, and QoL and use of inhaled corticosteroids and β2‐agonists was significantly decreased after 25 months of treatment in both groups.

Sublingual immunotherapy: a comprehensive review.