Studying NK cell/dendritic cell interactions.

  title={Studying NK cell/dendritic cell interactions.},
  author={Mathias Lucas and C{\'e}dric Vonarbourg and Peter Aichele and Andreas Diefenbach},
  journal={Methods in molecular biology},
Although NK cells were originally identified as "naturally" active cells believed to follow a cell-autonomous activation program, it is now widely accepted that NK cells need to interact with dendritic cells for their full functional activation and for their homeostasis. In this chapter, we will provide an experimental guide to the analysis of NK cell/DC interactions in vitro and in vivo. We have put special emphasis on the recently developed mouse models allowing the inducible and specific… CONTINUE READING