Corpus ID: 9473524

Study on the therapeutic effects of salicylazosulfapyridine on ulcerative colitis in rats

  title={Study on the therapeutic effects of salicylazosulfapyridine on ulcerative colitis in rats},
  author={Jun Qian and Yongtian Fan and Haiyang Feng and Z. Liu and L. Jiang},
Objective: To explore the therapeutic effects of salicylazosulfapyridine (SASP) on rats with ulcerative colitis (UC). Methods: The UC rat model was induced by coloclysis with TNBS (trinitrobenzene sulfonic acid)/alcohol. Thirty male SD rats were randomly divided into sham group, model group and SASP group with 10 rats in each group. During the two-week drug treatment, the weights, the intestinal mucosal injuries and the inflammation levels of rats in three different groups were recorded… Expand

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