Study on the role of patulin on pathogenicity and virulence of Penicillium expansum.

  title={Study on the role of patulin on pathogenicity and virulence of Penicillium expansum.},
  author={Simona Marianna Sanzani and Massimo Reverberi and Marta Punelli and Antonio Massimo Ippolito and Corrado Fanelli},
  journal={International journal of food microbiology},
  volume={153 3},
Although the antibacterial activity and toxicity to humans and animals of the mycotoxin patulin are well known, its role in the postharvest decay of apples by Penicillium expansum has never been investigated. In the present study the gene disruption technique was used to alter the sequence of 6-methyl-salicylic acid synthase, an enzyme involved in the first committed step of patulin biosynthesis. Thirty-nine mutants were obtained, however only two of them (M5 and M21) passed the sub-cultural… CONTINUE READING


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