Study on the pathophysiology of experimental Burkholderia pseudomallei infection in mice.

@article{Gauthier2001StudyOT,
  title={Study on the pathophysiology of experimental Burkholderia pseudomallei infection in mice.},
  author={Yves P Gauthier and Ralf Matthias Hagen and Guy Brochier and Heinrich Neubauer and W. D. Splettstoesser and E J Finke and Dominique R. Vidal},
  journal={FEMS immunology and medical microbiology},
  year={2001},
  volume={30 1},
  pages={53-63}
}
Burkholderia pseudomallei is the etiological agent of melioidosis, a potentially fatal disease occurring in man and animals. The aim of this study was to investigate the pathophysiological course of experimental melioidosis, and to identify the target organs, in an animal model. For this purpose SWISS mice were infected intraperitoneally with the virulent strain B. pseudomallei 6068. The bacterial load of various organs was quantified daily by bacteriological analysis and by an enzyme-linked… CONTINUE READING