Study on the pathogenesis of bluetongue: replication of the virus in the organs of infected sheep.

  title={Study on the pathogenesis of bluetongue: replication of the virus in the organs of infected sheep.},
  author={Alessandro Pini},
  journal={The Onderstepoort journal of veterinary research},
  volume={43 4},
  • Alessandro Pini
  • Published 1976 in The Onderstepoort journal of veterinary research
The pathogenesis of bluetongue infection was studied by the titration of the virus in tissue samples taken from sheep inoculated subcutaneously in the auricula of the ear with 76 TC ID50 of the plaque-purified type 10 bluetongue virus. Tissue samples were taken from individual animals killed at daily intervals over a period of 11 days. The mean incubation time was 6.9 days and the first clinical sign was pyrexia. On the 4th day, bluetongue virus was demonstrated in the lymph nodes of the… CONTINUE READING

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