Study on the mechanism of maternal imprinting during oocyte growth.

@article{Obata2011StudyOT,
  title={Study on the mechanism of maternal imprinting during oocyte growth.},
  author={Yayoi Obata},
  journal={The Journal of reproduction and development},
  year={2011},
  volume={57 1},
  pages={1-8}
}
  • Yayoi Obata
  • Published 2011 in The Journal of reproduction and development
In mammals, both parental genomes are essential for normal ontogeny because epigenetic modifications imposed in the parents' gametes lead to parent-of-origin specific gene expression in their offspring. These phenomena are referred to as genomic imprinting. It has been shown that maternal imprinting is established during oocyte growth, lack of maternal imprinting in zygotes leads to early embryonic death, and in vitro system that allows establishment of maternal imprinting is developed. In this… CONTINUE READING