Study on the bone marrow mesenchymal stem cells induced drug resistance in the U937 cells and its mechanism.

@article{Lin2006StudyOT,
  title={Study on the bone marrow mesenchymal stem cells induced drug resistance in the U937 cells and its mechanism.},
  author={Yu-mei Lin and Gui-zhen Zhang and Zong-xiang Leng and Zhen-xia Lu and Li-sha Bu and Shen Gao and Shao-juan Yang},
  journal={Chinese medical journal},
  year={2006},
  volume={119 11},
  pages={
          905-10
        }
}
BACKGROUND The hematopoietic microenvironment (HM) plays a critical role in malignant cell growth, patient survival, and response to chemotherapy in hematologic malignancies. However, mechanisms associated with this environmental influence remain unclear. In this study, we investigated the role of bone marrow derived mesenchymal stem cells (MSCs) in U937 cell line, to find out the relations between leukemia drug resistance and the MSCs. METHODS U937 cells were cultured in suspension or grew… 

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    Journal of biomedicine & biotechnology
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TLDR
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