Study on the Synthesis, Antioxidant Properties, and Self-Assembly of Carotenoid–Flavonoid Conjugates

@article{Lnzembold2020StudyOT,
  title={Study on the Synthesis, Antioxidant Properties, and Self-Assembly of Carotenoid–Flavonoid Conjugates},
  author={Ildik{\'o} L{\'i}nzembold and Dalma Czett and K. B{\"o}ddi and T. Kurt{\'a}n and S. B. Kiraly and Gergely Guly{\'a}s-Fekete and A. Tak{\'a}tsy and T. L{\'o}r{\'a}nd and J. Deli and A. Ag{\'o}cs and V. Nagy},
  journal={Molecules},
  year={2020},
  volume={25}
}
Flavonoids and carotenoids possess beneficial physiological effects, such as high antioxidant capacity, anticarcinogenic, immunomodulatory, and anti-inflammatory properties, as well as protective effects against UV light. The covalent coupling of hydrophobic carotenoids with hydrophilic flavonoids, such as daidzein and chrysin, was achieved, resulting in new amphipathic structures. 7-Azidohexyl ethers of daidzein and chrysin were prepared in five steps, and their azide-alkyne [4 + 2… Expand

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