Study on propionyl-L-carnitine in chronic heart failure.

  title={Study on propionyl-L-carnitine in chronic heart failure.},
  journal={European heart journal},
  volume={20 1},
  • Published 1999 in European heart journal
AIMS In patients with chronic heart failure, fatigue is independent of haemodynamic and neuroendocrine changes and possibly may be due to impaired muscle metabolism. Propionyl-L-carnitine, a carnitine derivative, was shown in previous studies to improve muscle metabolism. The objective of this study was to evaluate the effect of propionyl-L-carnitine on exercise capacity in mild moderate chronic heart failure patients, treated with ACE inhibitors and diuretics. METHODS AND RESULTS This was a… CONTINUE READING