Study on neutralization of low molecular weight heparin (LHG) by protamine sulfate and its neutralization characteristics.

@article{Sugiyama1992StudyON,
  title={Study on neutralization of low molecular weight heparin (LHG) by protamine sulfate and its neutralization characteristics.},
  author={Tomomi Sugiyama and M. Itoh and Masaki Ohtawa and T Natsuga},
  journal={Thrombosis research},
  year={1992},
  volume={68 2},
  pages={119-29}
}
The neutralizing effects of protamine sulfate (PS) on anticoagulant activities of low molecular weight heparin (LHG) and conventional sodium heparin (Heparin) were investigated. The in vitro anti-factor Xa and APTT-prolonging activities of Heparin were almost completely neutralized by PS, whereas the activities of LHG remained partially intact in the… CONTINUE READING