Corpus ID: 23299302

Study on in vitro cytotoxicity and in vivo antitumor effect of nanoliposomes containing oridonin

@inproceedings{Wang2008StudyOI,
  title={Study on in vitro cytotoxicity and in vivo antitumor effect of nanoliposomes containing oridonin},
  author={Chuan-jin Wang and Yunyang Wei and Li Yu and L. Zhang},
  year={2008}
}

• Chuan-jin Wang, Yunyang Wei, +1 author L. Zhang
• Published 2008
• Medicine

Aim: To compare the cytotoxic effect in vitro and antitumor effect in vivo of oridonin nanoliposomes injection(O-NL) and free oridonin solution(O-F). Methods The cytotoxic effect of O-NL and O-F against HePG-2 and MGC-803 cells in vitro were studied by MTT assay method. The antitumor effect studies in vivo of O-NL and O-F were performed in murine heptocarcinoma H22 tumor-bearing mice after iv administration through the tail vein. Results Liposomal encapsulation improved the in vitro cytotoxic… Expand

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