Corpus ID: 1369550

Study on immunomodulatory activity of ethanolic extract of Spilanthes acmella Murr. leaves.

@article{Savadi2010StudyOI,
  title={Study on immunomodulatory activity of ethanolic extract of Spilanthes acmella Murr. leaves.},
  author={Rudraprabhu Savadi and Rajesh Kumar Yadav and Nita Yadav},
  journal={Indian Journal of Natural Products and Resources},
  year={2010},
  volume={1},
  pages={204-207}
}
The leaves of Spilanthes acmella Murr. have been used traditionally as tonic and in the treatment of rheumatism, gout, sailagogine and claimed to possess immunostimulant activity. In the present study, the ethanolic extract (500mg/kg bwt p.o.) of its leaves was evaluated for immunomodulatory activity using various models like modulation of macrophage function (morphometric and functional changes in mice), carbon clearance assay with the help of Indian ink dispersion (0.5ml/100g bwt i.v.) in… Expand
nopr.niscair.res.in
29 Citations
Background Citations
11

Tables from this paper

29 Citations

Citation Type

Citation Type

Immunomodulation Potential of Andrographis Paniculata and Tinospora Cordifolia Methanolic Extracts in Combination Forms
Objective: This work mainly focuses on the immunomodulatory effect of different drug combinations (DC-I to DC-V) of methanolic extracts of aerial parts of Andrographis paniculata (AP) and mature… Expand
Intestinal cestodes of chicken are effectively killed by quinoline-rich extract of Spilanthes acmella
TLDR
The efficacy of S. acmella extract and structural damages it caused on the cestode indicates that it is a potential source of anthelmintic agent and that 2,2,4-trimethyl-1,2-dihydroquinoline contributes to its antiparasitic activity. Expand
Isolation of spilanthol from Acmella oleracea based on Green Chemistry and evaluation of its in vitro anti-inflammatory activity
Abstract Acmella oleracea (jambu) is a South American plant whose pharmacological properties include antimalarial, anesthetic, and anti-inflammatory activities. However, the compounds contributing to… Expand
Phytochemical investigations on the medicinal plant Acmella oleracea cultivated in Mizoram , India
Species of the genus Acmella are perennial plants and are well known as traditional medicines and as vegetables in tropical regions. Of these, A. oleracea (L.) R.K. Jansen is the most widely used,… Expand
Evaluation of the effectiveness of Acmella uliginosa (Sw.) Cass. flower methanolic extract in pain amelioration and memory impairment in the experimental rat models: Search for an alternative remedy over opioid painkillers
TLDR
The results indicate that the AU flower methanolic extract qualifies as a potent painkiller and overcomes the disadvantages of opioid analgesics. Expand
Assessment of anti-inflammatory and anti-arthritic properties of Acmella uliginosa (Sw.) Cass. based on experiments in arthritic rat models and qualitative gas chromatography-mass spectrometry analyses
TLDR
The findings indicated that the crude flower homogenate of AU contains potential anti- inflammatory compounds which could be used as an anti-inflammatory/anti-arthritic medication. Expand
Spilanthes acmella ethanolic flower extract: LC-MS alkylamide profiling and its effects on sexual behavior in male rats.
TLDR
The orally administered ethanolic extracts of the Spilanthes acmella flower had a dose dependent positive effect on mounting frequency, intromission frequency and ejaculation frequency and the most significant effects were observed at 150mg/kg treatment, even after a lapse of 7 and 14 days of discontinuance of drug treatment. Expand
Chemical composition and broad-spectrum anthelmintic activity of a cultivar of toothache plant, Acmella oleracea, from Mizoram, India
TLDR
Acmella oleracea contains important bioactive compounds, which are responsible for the broad-spectrum anthelmintic activity on intestinal parasites, and is used by the Mizo people of India and Myanmar for intestinal helminthiasis. Expand
Anthelmintic activity of praziquantel and Spilanthes acmella extract on an intestinal cestode parasite
TLDR
Findings indicate that S. acmella is a good source of compounds with anthelmintic activity, and that PZQ was more potent, but the plant extract was also effective at all concentrations tested. Expand
A REVIEW O PHYTOPHARMACOLOGY AD MICROPROPAGATIO OF SPILATHES ACMELLA
TLDR
The bioactive constituents isolated from S. acmella are spilanthol, isobutylamides, triterpenoids, butylated hydroxytoluene, polygo� dial and eudesmanolide etc. Expand
...
1
2
3
...

References

SHOWING 1-10 OF 14 REFERENCES
Preliminary studies on the immunomodulatory and antioxidant properties of Selaginella species
TLDR
Out of the three Selaginella species studied, the water extract of S. involvens has promising thymus growth stimulatory activity in adult mice and remarkable antilipid peroxidation property; these observations are of interest in view of tribal and folklore belief that this plant prolongs life span. Expand
The Essential Oil of Spilanthes acmella Murr.
ABSTRACT Eighteen compounds have been characterized by GC/MS and Kovats indices in the essential oil of Spilanthes acmella. The major constituents identified were β-caryophyllene (30.2%), γ-cadinene… Expand
Analysis of the free amino acid content in pollen of nine Asteraceae species of known allergenic activity.
TLDR
The study reports the free amino acid composition of the pollen of nine members of the family Asteraceae, i.e. Ageratum conyzoides, Gnaphalium indicum, Mikania scandens Willd, Parthenium hysterophorus, Spilanthes acmella Murr, Vernonia cinerea (L.) Lees, and Xanthium strumarium by thin layer chromatography. Expand
Practical pharmacognosy techniques and experiments
Fundamentals of experimental pharmacology
Immunopotentiating activity of Immune-2, a polyherbal product
  • Indian J Pharmacology,
  • 1998
Medicinal plants of India
Induced morphometric and functional changes in mouse peritoneal macrophages
  • Phytother Res,
  • 1995
Two Sesquiterpenes from Spilanthes acmella L.
PHYTOCHEMICAL EXAMINATION OF SPILANTHUS ACEMELLA (MURR.)
...
1
2
...