Study on immunomodulatory activity of ethanolic extract of Spilanthes acmella Murr. leaves.
@article{Savadi2010StudyOI, title={Study on immunomodulatory activity of ethanolic extract of Spilanthes acmella Murr. leaves.}, author={Rudraprabhu Savadi and Rajesh Kumar Yadav and Nita Yadav}, journal={Indian Journal of Natural Products and Resources}, year={2010}, volume={1}, pages={204-207} }
The leaves of Spilanthes acmella Murr. have been used traditionally as tonic and in the treatment of rheumatism, gout, sailagogine and claimed to possess immunostimulant activity. In the present study, the ethanolic extract (500mg/kg bwt p.o.) of its leaves was evaluated for immunomodulatory activity using various models like modulation of macrophage function (morphometric and functional changes in mice), carbon clearance assay with the help of Indian ink dispersion (0.5ml/100g bwt i.v.) in…
33 Citations
COMPARISON OF IMMUNOMODULATORY ACTIVITY OF ANDROGRAPHIS PANICULATA AND TINOSPORA CORDIFOLIA
- Medicine
- 2016
It is concluded that Andrographis paniculata exhibited best immunostimulant potential, indicating that it has promising immunomodulatory activity, as proposed from commercial point of view.
Immunomodulation Potential of Andrographis Paniculata and Tinospora Cordifolia Methanolic Extracts in Combination Forms
- Medicine
- 2016
Results suggest that although all the five tested combinations prepared using different proportion of methanol extracts of A. paniculata and T. cordifolia showed a significant increase in macrophase count, neutrophil adhesion, haemagglutinating antibody titre and delayed type hypersensitivity response, combination DC-II exhibited best immunostimulant potential, indicating that it has promising immunomodulatory activity.
Intestinal cestodes of chicken are effectively killed by quinoline-rich extract of Spilanthes acmella
- BiologyVeterinary world
- 2019
The efficacy of S. acmella extract and structural damages it caused on the cestode indicates that it is a potential source of anthelmintic agent and that 2,2,4-trimethyl-1,2-dihydroquinoline contributes to its antiparasitic activity.
Isolation of spilanthol from Acmella oleracea based on Green Chemistry and evaluation of its in vitro anti-inflammatory activity
- ChemistryThe Journal of Supercritical Fluids
- 2018
Phytochemical investigations on the medicinal plant Acmella oleracea cultivated in Mizoram , India
- 2017
Species of the genus Acmella are perennial plants and are well known as traditional medicines and as vegetables in tropical regions. Of these, A. oleracea (L.) R.K. Jansen is the most widely used,…
Evaluation of the effectiveness of Acmella uliginosa (Sw.) Cass. flower methanolic extract in pain amelioration and memory impairment in the experimental rat models: Search for an alternative remedy over opioid painkillers
- MedicinePharmacognosy Magazine
- 2019
The results indicate that the AU flower methanolic extract qualifies as a potent painkiller and overcomes the disadvantages of opioid analgesics.
Assessment of anti-inflammatory and anti-arthritic properties of Acmella uliginosa (Sw.) Cass. based on experiments in arthritic rat models and qualitative gas chromatography-mass spectrometry analyses
- BiologyJournal of intercultural ethnopharmacology
- 2016
The findings indicated that the crude flower homogenate of AU contains potential anti- inflammatory compounds which could be used as an anti-inflammatory/anti-arthritic medication.
Spilanthes acmella ethanolic flower extract: LC-MS alkylamide profiling and its effects on sexual behavior in male rats.
- BiologyPhytomedicine : international journal of phytotherapy and phytopharmacology
- 2011
Chemical composition and broad-spectrum anthelmintic activity of a cultivar of toothache plant, Acmella oleracea, from Mizoram, India
- Medicine, BiologyPharmaceutical biology
- 2020
Acmella oleracea contains important bioactive compounds, which are responsible for the broad-spectrum anthelmintic activity on intestinal parasites, and is used by the Mizo people of India and Myanmar for intestinal helminthiasis.
Anthelmintic activity of praziquantel and Spilanthes acmella extract on an intestinal cestode parasite
- BiologyActa pharmaceutica
- 2020
Findings indicate that S. acmella is a good source of compounds with anthelmintic activity, and that PZQ was more potent, but the plant extract was also effective at all concentrations tested.
References
SHOWING 1-10 OF 14 REFERENCES
The Essential Oil of Spilanthes acmella Murr.
- Chemistry
- 1991
ABSTRACT Eighteen compounds have been characterized by GC/MS and Kovats indices in the essential oil of Spilanthes acmella. The major constituents identified were β-caryophyllene (30.2%), γ-cadinene…
Analysis of the free amino acid content in pollen of nine Asteraceae species of known allergenic activity.
- Biology, MedicineAnnals of agricultural and environmental medicine : AAEM
- 1998
The study reports the free amino acid composition of the pollen of nine members of the family Asteraceae, i.e. Ageratum conyzoides, Gnaphalium indicum, Mikania scandens Willd, Parthenium hysterophorus, Spilanthes acmella Murr, Vernonia cinerea (L.) Lees, and Xanthium strumarium by thin layer chromatography.
Preliminary studies on the immunomodulatory and antioxidant properties of Selaginella species
- Biology
- 2005
Out of the three Selaginella species studied, the water extract of S. involvens has promising thymus growth stimulatory activity in adult mice and remarkable antilipid peroxidation property; these observations are of interest in view of tribal and folklore belief that this plant prolongs life span.
Quantitative study of the granulopectic activity of the reticulo-endothelial system. II. A study of the kinetics of the R. E. S. in relation to the dose of carbon injected; relationship between the weight of the organs and their activity.
- MedicineBritish journal of experimental pathology
- 1953
Immunopotentiating activity of Immune-2, a polyherbal product
- Indian J Pharmacology,
- 1998