Corpus ID: 101263556

Study on determination of triptolide in human plasma by HPLC-MS

@inproceedings{Shenghao2005StudyOD,
  title={Study on determination of triptolide in human plasma by HPLC-MS},
  author={T. Sheng-hao and Chen Hong-bo and Tan Zhi-rong and H. Yonghong},
  year={2005}
}
OBJECTIVE To establish a method for the determination of triptolide in human plasma by HPLC/MS. METHODS Use Thermo-keystone Hypurity C_(18) column (150×(2.1) mm, 5μm);the mobile phase was methanol-water (30∶70) with a flow rate of (0.2) mL∶min~(-1); column temperature (40 ℃). A Finnigan LCQ Deca XP TM with an atmospheric pressure chemical ionization (APCI) source was used as detector and was operated in positive ion mode. Selected reaction monitoring (SRM) was used and transitions selected for… Expand