Study on degradation kinetics of 2-(2-hydroxypropanamido) benzoic acid in aqueous solutions and identification of its major degradation product by UHPLC/TOF-MS/MS.

  • Qili Zhang, Jiao Guan, Rong Rong, Yunli Zhao, Zhiguo Yu
  • Published 2015 in Journal of pharmaceutical and biomedical analysis

Abstract

A RP-HPLC method was developed and validated for the degradation kinetic study of 2-(2-hydroxypropanamido) benzoic acid (HPABA), a promising anti-inflammatory drug, which would provide a basis for further studies on HPABA. The effects of pH, temperature, buffer concentration and ionic strength on the degradation kinetics of HPABA were discussed… (More)
DOI: 10.1016/j.jpba.2015.04.012

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Cite this paper

@article{Zhang2015StudyOD, title={Study on degradation kinetics of 2-(2-hydroxypropanamido) benzoic acid in aqueous solutions and identification of its major degradation product by UHPLC/TOF-MS/MS.}, author={Qili Zhang and Jiao Guan and Rong Rong and Yunli Zhao and Zhiguo Yu}, journal={Journal of pharmaceutical and biomedical analysis}, year={2015}, volume={112}, pages={1-7} }