Study on absorption of indomethacin from sustained-release suppositories containing hydrogenated soybean lecithin in rabbits.

@article{Nakajima1989StudyOA,
  title={Study on absorption of indomethacin from sustained-release suppositories containing hydrogenated soybean lecithin in rabbits.},
  author={Takeshi Nakajima and Yuuki Takashima and Atsushi Furuya and Yasuaki Ozawa and Yoshiaki Kawashima},
  journal={Chemical & pharmaceutical bulletin},
  year={1989},
  volume={37 11},
  pages={3145-7}
}
The absorption of indomethacin (IM) from suppositories containing hydrogenated soybean lecithin (HL) after rectal administration in rabbits was investigated with the aim of producing sustained-release suppositories. The suppositories were prepared by the fusion method with IM, HL and Witepsol H-15 (H-15). The IM release rate from the suppositories (IM 10 mg… CONTINUE READING