Study of urinary proteomes in Anderson-Fabry disease.

  title={Study of urinary proteomes in Anderson-Fabry disease.},
  author={Lucie Vojtov{\'a} and Tom{\'a}{\vs} Zima and Vladim{\'i}r Tesař and Jana Michalov{\'a} and Petr Prikryl and Gabriela Dost{\'a}lov{\'a} and Ale{\vs} Linhart},
  journal={Renal failure},
  volume={32 10},
BACKGROUND Anderson-Fabry disease (AFD) is an X-linked genetic disorder with deficient α-galactosidase A activity. The main aim of this work was to investigate possible differences in urine proteins between healthy controls and AFD patients and to identify abnormal proteins as potential biomarkers of disease. MATERIAL AND METHODS We studied 2D electrophoresis images of urine samples collected from AFD patients and healthy subjects. The proteins were separated using isoelectric focusing method… CONTINUE READING