Study of tricarboxylic acid cycle flux changes in human visual cortex during hemifield visual stimulation using (1)H-[(13)C] MRS and fMRI.

Abstract

The relationships between brain activity and accompanying hemodynamic and metabolic alterations, particularly between the cerebral metabolic rate of oxygen utilization (CMR(O2)) and cerebral blood flow (CBF), are not thoroughly established. CMR(O2) is closely coupled to the rate of tricarboxylic acid (TCA) cycle flux. In this study, the changes in glutamate… (More)

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@article{Chen2001StudyOT, title={Study of tricarboxylic acid cycle flux changes in human visual cortex during hemifield visual stimulation using (1)H-[(13)C] MRS and fMRI.}, author={W Chen and X H Zhu and Rolf Gruetter and Elizabeth R. Seaquist and Gregory Adriany and Kamil Ugurbil}, journal={Magnetic resonance in medicine}, year={2001}, volume={45 3}, pages={349-55} }