Study of the response of superoxide dismutase in mouse organs to radon using a new large-scale facility for exposing small animals to radon.

@article{Kataoka2011StudyOT,
  title={Study of the response of superoxide dismutase in mouse organs to radon using a new large-scale facility for exposing small animals to radon.},
  author={Takahiro Kataoka and Akihiro Sakoda and Yuu Ishimori and Teruaki Toyota and Yuichi Nishiyama and Hiroshi Tanaka and Fumihiro Mitsunobu and Kiyonori Yamaoka},
  journal={Journal of radiation research},
  year={2011},
  volume={52 6},
  pages={775-81}
}
We examined dose-dependent or dose rate-dependent changes of superoxide dismutase (SOD) activity using a new large-scale facility for exposing small animals to radon. Mice were exposed to radon at a concentration of 250, 500, 1000, 2000, or 4000 Bq/m(3) for 0.5, 1, 2, 4, or 8 days. When mice were exposed to radon at 2000 day•Bq/m(3), activation of SOD activities in plasma, liver, pancreas, heart, thymus, and kidney showed dose-rate effects. Our results also suggested that continuous exposure to… CONTINUE READING