Study of the relationship between gene polymorphisms of paraoxonase 2 and stroke in a Chinese population.

@article{Xu2008StudyOT,
  title={Study of the relationship between gene polymorphisms of paraoxonase 2 and stroke in a Chinese population.},
  author={Hong-wei Xu and Ning Yuan and Zhen Zhao and Le Zhang and Jian Bai Xia and K Zeng and Bo Xiao and Xiao-su Yang and Bei-sha Tang},
  journal={Cerebrovascular diseases},
  year={2008},
  volume={25 1-2},
  pages={87-94}
}
BACKGROUND AND PURPOSE The paraoxonase (PON) gene family has been demonstrated to be capable of preventing lipid peroxidation and could consequently exert antiatherosclerotic effects. Alteration of enzyme activity due to polymorphisms in the PON genes may influence the development of atheroma and thus affect stroke risk. PON2, the second member of this family, has two polymorphisms, C311S and G148A. Our study explores the relationship between the two polymorphisms of PON2 and stroke. METHODS… CONTINUE READING
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