Study of the luteinizing hormone-induced increase of ovarian blood flow during the estrous cycle in the rat.

@article{Varga1985StudyOT,
  title={Study of the luteinizing hormone-induced increase of ovarian blood flow during the estrous cycle in the rat.},
  author={Bertalan Varga and Edit Horvath and G. Folly and E Stark},
  journal={Biology of reproduction},
  year={1985},
  volume={32 3},
  pages={
          480-8
        }
}
CYF rats were anesthetized on various days of the 4-day cycle and blood samples were collected at 5-min interals from the ovarian vein before and after i.v. administration of 5 micrograms/100 g BW of luteinizing hormone (LH). Ovarian venous outflow, blood pressure and hematocrit were continuously recorded, and from the blood samples progesterone (P) and 17 beta-estradiol (E2) were determined by radioimmunoassay (RIA). Ovarian blood flow and P secretion showed a parallel increase on Day 1… 
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Effect of GnRH and hCG on progesterone concentration and ovarian and luteal blood flow in diestrous mares.
Acute effects of cadmium on preovulatory serum FSH, LH, and prolactin levels and on ovulation and ovarian hormone secretion in estrous rats.
Stimulation of LH, FSH, and luteal blood flow by GnRH during the luteal phase in mares.
Genital blood flow and endometrial gene expression during the preovulatory period after Prostaglandin F(2alpha)-induced luteolysis in different luteal phases in cows.
TLDR
Results show that follicular and uterine perfusion during the ovulatory phase are higher after induction of luteolysis during the 1(st) follicular wave compared with the 2(nd) wave or intact cycle.
Effects of induction of ovulation with GnRH or HCG on follicular and luteal blood flow in Holstein-Friesian heifers.
TLDR
It is suggested that induction of ovulation with hCG and GnRH has a temporary effect on FBF and oestrogen levels while no effect on the size of corpora lutea, LBF and P(4) levels was observed.
Involvement of prostaglandins in LH-induced superovulation in the cyclic hamster.
Effect of Human Chorionic Gonadotropin on Reproductive Organ Blood Flow in Cycling Rats
TLDR
High doses of hCG given clinically may decrease uterine flow and potentially lead to implantation failure, and the results indicate an organ specific, dose-dependent blood flow response to hCG in cycling rats, which appears, in the case of uterusine flow, to be attenuated by removal of the ovaries.
Altered ovarian progesterone secretion induced by cadmium fails to interfere with embryo transport in the oviduct of the rat.
Vascular control of ovarian function: ovulation, corpus luteum formation and regression.
Uptake and distribution of Cd in the ovaries, adrenals, and pituitary in pseudopregnant rats: effect of Cd on progesterone serum levels.
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References

SHOWING 1-10 OF 28 REFERENCES
Effects of the luteinizing hormone on blood flow in the follicular rabbit ovary, as measured by radioactive microspheres.
  • P. Janson
  • Medicine, Biology
    Acta endocrinologica
  • 1975
TLDR
Ovarian blood flow was determined before and after a single intravenous injection of LH to anaesthetized, post-pubertal virgin rabbits, using 15 plus or minus 5 mum microspheres, labelled with Ytterbium-169 and Scandium-46 to study the mechanism of the LH induced ovarian vasodilatation.
Cyclic changes in utero-ovarian blood flow and ovarian hormone secretion in the hamster: effects of adrenocorticotropin, luteinizing hormone, and follicle-stimulating hormone.
These experiments were designed to determine utero-ovarian vein blood flow and ovarian secretion rates and the ability of ACTH, LH, or FSH to modify these parameters in the cyclic hamster. Hamsters…
Ovarian venous outflow, progesterone and 17 beta-oestradiol secretion and peripheral blood level during pregnancy in the rat.
TLDR
The high level of ovarian blood flow and progesterone secretion in mid-pregnancy is suggested to be the result of the stimulation of luteotropic material originating from the placenta.
Ovarian Blood Flow in the Rat: Association with Body Weight, the Estrous Cycle, and Pseudopregnancy 1
  • D. Garris, T. Curry
  • Biology
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine
  • 1983
TLDR
The results indicate that during the estrous cycle, OBF rates and serum E2 levels rise in a parallel manner, whereas during PSP, serum P levels and OBF are positively correlated.
Increase of ovarian progesterone secretion by beta 2-adrenergic stimulation in oestrous rats.
TLDR
It is suggested that ovarian beta 2-adrenergic receptors have a regulatory role in ovarian hormone secretion and fenoterol administered iv increased P secretion without altering ovarian blood flow, whereas noradrenaline and isoproterenol had no effect on P secretion.
AN EFFECT OF LUTEINIZING HORMONE ON THE FRACTIONAL PERFUSION OF THE RAT OVARY.
TLDR
The 42K method of Sapirstein has been modified to estimate the effect of gonadotropins on ovarian fractional blood flow, and it is possible that one function of this hormone involves the cyclic regulation of ovarian blood flow.
Inhibition by indomethacin of ovulation induced by human chorionic gonadotrophin in immature rats primed with pregnant mare serum gonadotrophin.
TLDR
It was concluded that prostaglandins may mediate the action of HCG on ovulation through two mechanisms which operate at different stages of the preovulatory process.
Peripheral levels of estrogen in the cyclic hamster.
TLDR
The day 4 peak in E2 was temporally related to the preovulatory surge in LH and an abrupt increase in ovarian progesterone, whereas the addition of 5 μg of LH restored E2 to normal values.
Mechanism of luteinizing hormone regulation of prostaglandin synthesis in rat granulosa cells.
TLDR
Results indicate that LH acts at a step in the prostaglandin pathway after hydrolysis of arachidonic acid esters and produces an increase in prostag landin synthetase activity.
Role of prostaglandin E2 in the stimulatory effect of ACTH on ovarian blood flow.
  • E. Stark, B. Varga
  • Medicine, Biology
    Acta medica Academiae Scientiarum Hungaricae
  • 1975
TLDR
It is suggested that in dogs ACTH exerts its ovarian blood flow stimulatory effect by releasing PGE2 or some similar agent(s), and the effect of both agents can be characterized by a common equation.
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