Study of the local immune response to Fasciola hepatica in the liver and hepatic lymph nodes of goats immunised with a peptide of the Sm14 antigen.

@article{Zafra2009StudyOT,
  title={Study of the local immune response to Fasciola hepatica in the liver and hepatic lymph nodes of goats immunised with a peptide of the Sm14 antigen.},
  author={Rafael G{\'o}mez Zafra and Leandro Buffoni and Rafael A P{\'e}rez-Ecija and Ricardo Evandro Mendes and Alvaro Mart{\'i}nez-Moreno and Francisco Javier Mart{\'i}nez-Moreno and Jos{\'e} P{\'e}rez},
  journal={Research in veterinary science},
  year={2009},
  volume={87 2},
  pages={226-32}
}
The nature of the local immune response was assessed studying the distribution of CD2(+), CD4(+), CD8(+), gammadelta(+) T lymphocytes, IgM(+) B cells, IL-4(+) and IFN-gamma(+) cells in the liver and hepatic lymph nodes (HLN) of goats immunised with a synthetic peptide of the Sm14 antigen from Schistosoma mansoni and challenged with Fasciola hepatica. A morphometric study of HLN was also carried out in order to evaluate the hyperplasia of lymphoid follicles. Despite the decrease in fluke burdens… CONTINUE READING

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