Study of the effect of Allium porrum on hypertension induced in rats
@article{Badary2013StudyOT, title={Study of the effect of Allium porrum on hypertension induced in rats}, author={Osama A Badary and Nemat A. Z. Yassin and Siham Mostafa El-Shenawy and Mostafa Abd EL-Moneem and Hanan M. AL-Shafeiy}, journal={Revista Latinoamericana de Qu{\'i}mica}, year={2013}, volume={41}, pages={149-160} }
El presente estudio fue disenado para investigar el efecto del extracto alcoholico de Allium porrum (250 y 500mg/kg) en la hipertension inducida experimentalmente en ratas machos por la administracion oral del L-NG-nitroarginina metil ester(L-NAME) (50mg/kg / dia) durante cuatro semanas sucesivas. El extracto alcoholico de Allium porrum (250 y 500 mg/kg) se administro por via oral diariamente 8 semanas previas a la induccion de la hipertension y 4 semanas simultaneamente con L-NAME. La presion…
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References
SHOWING 1-10 OF 42 REFERENCES
Effect of pioglitazone on L-NAME induced hypertension in diabetic rats.
- Biology, MedicineVascular pharmacology
- 2005
Lisinopril attenuates renal oxidative injury in l-NAME-induced hypertensive rats
- BiologyMolecular and Cellular Biochemistry
- 2011
It is suggested that lisinopril could diminish biochemical alterations in l-NAME induced hypertensive renal damage that occurs by oxidative stress.
Hypolipidemic activity of Allium porrum L. in cholesterol-fed rabbits.
- Chemistry, MedicineJournal of medicinal food
- 2006
Findings indicate that this plant may be useful for the treatment of hypercholesterolemia, and changes in the distribution of cholesterol in HDL or LDL were found, and LDL cholesterol decreased significantly in all of the groups treated with A. porrum extract.
Lipid lowering effect of S-methyl cysteine sulfoxide from Allium cepa Linn in high cholesterol diet fed rats.
- Biology, ChemistryJournal of ethnopharmacology
- 2007
Garlic prevents hypertension induced by chronic inhibition of nitric oxide synthesis.
- BiologyLife sciences
- 1998
The role of inflammatory markers in the cardioprotective effect of L-carnitine in L-NAME-induced hypertension.
- Biology, MedicineAmerican journal of hypertension
- 2008
The chronic administration of LC reduces blood pressure and attenuates the inflammatory process associated with arterial hypertension.
Cholesterol-lowering effect of garlic extracts and organosulfur compounds: human and animal studies.
- ChemistryThe Journal of nutrition
- 2001
The results of these studies indicate that the cholesterol-lowering effects of garlic extract, such as AGE, stem in part from inhibition of hepatic cholesterol synthesis by water-soluble sulfur compounds, especially SAC.
Feeding rats the nitric oxide synthase inhibitor, L-N(omega)nitroarginine, elevates serum triglyceride and cholesterol and lowers hepatic fatty acid oxidation.
- BiologyThe Journal of nutrition
- 1996
The results suggest that the lower nitric oxide level in rats fed L-NNA leads to hyperlipidemia and that the elevation in serum triglyceride might be due to reduced fatty acid oxidation.
Comparative pharmacological investigations of Allium ursinum and Allium sativum.
- Biology, MedicinePlanta medica
- 1992
In the 5-LO and CO test the garlic extracts are slightly superior to the wild garlic extracts whereas, in the TA test, no differences could be found, underline the usefulness of wild garlic as a substitute of garlic.
Effect of allicin from garlic powder on serum lipids and blood pressure in rats fed with a high cholesterol diet.
- Biology, MedicineProstaglandins, leukotrienes, and essential fatty acids
- 2000
Results show that garlic is beneficial in reducing blood cholesterol, triglycerides levels and systolic blood pressure in hypercholesterolemic rats and may beneficially affect two risk factors for atherosclerosis--hyperlipidemia and hypertension.